Hans-Heiner Gorris
Academic studies and career:
1994 - 2001 Diploma in Biology, University of Münster (Germany) and University of York (England)
2001 - 2005 PhD, University of Lübeck (Germany)
2006 - 2009 Postdoctoral Fellow, Department of Chemistry, Tufts University, Medford (USA)
since 2009 Assistant Professor at the Institute of Analytical Chemistry, Chemo- und Biosensors, University of Regensburg (Germany); habilitation in 201
Research interests:
(1) Femtoliter Arrays: Single molecule analysis of enzyme kinetics; multiplexed assays.
(2) Upconverting nanoparticles: Background-free luminescent labeling for bioassays and bioimaging; Ratiometric encoding strategies.
(3) Luminescent sensing: Ratiometric measurements of enzyme activities, oxygen and other (bio-)analytes.
Awards and memberships:
(1) Heisenberg Fellowship of the German Research Council (2016-2018).
(2) Chair of the "European Upconversion Network" (COST Action CM1403), a transnational consortium of 22 European countries.
Selected publications:
(1) Liebherr RB, Renner M, Gorris HH (2014): A single molecule perspective on the functional diversity of in vitro-evolved β-glucuronidase. JACS 136, 5949-5955.
(2) Hlaváček A, Sedlmeier A, Skládal, P, Gorris HH (2014): Electrophoretic characterization and purification of silica-coated photon-upconverting nanoparticles and their bioconjugates. ACS Appl. Mater. Interfaces 6, 6930-6935.
(3) Gorris HH, Ali R, Saleh SM, Wolfbeis OS (2011): Tuning the dual emission of photon-upconverting nanoparticles for ratiometric multiplexed encoding. Adv. Mater. 23, 1652-1655.
(4) Gorris HH, Walt DR (2009): Mechanistic aspects of horseradish peroxidase elucidated through single-molecule studies. JACS 131, 6277-6282.
(5) Gorris HH, Rissin DM, Walt DR (2007): Stochastic inhibitor release and binding from single-enzyme molecules. PNAS 104, 17680-17685.
